CHDI Foundation
CHDI x Proteros Biostructures
Dedicated to developing safe, effective therapeutics for Huntington’s Disease, CHDI are a privately-funded, nonprofit who fund and collaborate with academic researchers, biotechs, and pharmaceutical companies, on a global scale.
As a nonprofit organization, CHDI act as a ‘collaborative enabler’ ensuring access to resources such as clinical data and bio samples, assays, reagents, antibodies, and more, are available to any research teams, removing the typical barriers they face. We are in a partnership with CHDI to help them with this process.

in collaboration with CHDI
Identification of a Potent, Selective, and Brain-Penetrant Rho Kinase Inhibitor and its Activity in a Mouse Model of Huntington’s Disease
Optimization of linear and cyclic peptide inhibitors of KEAP1-NRF2 protein-protein interaction
Combined Peptide and Small-Molecule Approach toward Nonacidic THIQ Inhibitors of the KEAP1/NRF2 Interaction
Accelerated epigenetic aging involves polycomb repressive complexes in Huntington’s disease