Gene-To-Protein

"Fit-for-function" Proteins

For a protein to be "fit-for-function" and work in your experiment it needs more than just a Purity %.

 It needs to have the right functionality, right construct, right homogeneity, right post-translational modifications, right complex composition, right stability, right species, right activity and right purity as well.

We don't just make protein, we understand the downstream applications and deliver the RIGHT protein.

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Proteins, Structures and Assays

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Gene-To-Protein Process

The Proteros Protein Science Project Process covers

 

Construct Design

  • Secondary structure prediction and 3-D modelling
  • Disorder Predictions
  • Crystal packing engineering
  • Secretion signal peptides

Gene Synthesis

  • Length variants
  • Deletions / insertions
  • Point mutations
  • Chimeric variants
  • Artificial protease recognition sites
  • Surrogates

Expression

Full suite of expression systems:

  • E. coli
  • Yeast
  • Insect cells
  • Mammalian cells

Purification

  • Full suite of chromatographic purification techniques
  • Analytical-data-driven purification
  • Dedicated lab space for "endotoxin-free" purification

Quality control

Identity / Functionality / Purity / Species / Activity / Stability / Homogeneity / PT modifications / Conjugate / Complex composition / Quantity / Endotoxin-level / Crystallizability

Product and Data Delivery

  • Prompt delivery of "fit-for-function" grade protein
  • Data package covering agreed quality metrics
  • Product Information Sheet

Proteros Statistics

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Pharma and biotech partners

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Peer-reviewed publications

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Protein projects completed

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Gallery proteins